Matthew A. Cottam, PhD

Matthew A. Cottam, PhD

Bioinformatics Analyst

Vanderbilt University

About Me

I am a bioinformatics analysis with experience across the gambit of modern next-generation sequencing technologies. The growth of transcriptomics and explosion of single cell sequencing modalities has enabled basic and clinical scientists to ask very intriguing questions, but design, analysis, and subsequent interpretation of single cell experiments is an ongoing challenge. In my current role, I offer consulting services to provide rapid and accurate analysis of sequencing results. I work collaboratively with researchers to understand their biological questions and work directly with them from raw data to publication.

Interests
  • Bioinformatics
  • R
  • Python
  • scSeq
  • Epigenetics
  • Immunology
Education
  • PhD in Molecular Physiology and Biophysics, 2022

    Vanderbilt University

  • BSc in Chemistry, 2016

    Wake Forest University

Skills

seqnew
Single Cell Sequencing
R
Python
cellnew
Flow Cytometry
mousenew
Mouse Models
scicomnew
Science Communication

Experience

 
 
 
 
 
Vanderbilt University
Bioinformatics Analyst
Jul 2016 – Present Nashville, TN
Bioinformatics shared resource core providing bioinformatics research services.
 
 
 
 
 
Vanderbilt University
PhD Molecular Physiology and Biophysics
Aug 2016 – Jun 2022 Nashville, TN
Lab of Dr. Alyssa Hasty. Department of Molecular Physiology and Biophysics.
 
 
 
 
 
Wake Forest University
B.S. Chemistry
Aug 2012 – May 2016 Winston-Salem, NC
Conducted undergraduate research with Dr. Michael Gross investigating gas exchange across high surface area solid-oxide fuel cell electrodes.

Honors and Awards

Ruth L. Kirschstein National Research Service Aware (F31)
The role of T cells in adipose tissue inflammation and insulin resistance during weight cycling
Dean’s Award for Exceptional Achievement for Advanced Students
This Dean’s award recognizes and supports outstanding graduate students who have distinguished themselves through the originality, significance and rigor of their dissertation research.
See certificate

Recent Posts

Projects

MAIseq

MAIseq

I built and maintain MAIseq, an interactive open-access data portal for exploring a multiomic Murine Adipose Immune cell dataset.

Featured Publications

Exercise and Adipose Tissue Immunity: Outrunning Inflammation
ROS-Degradable Polythioketal Urethane Foam Dressings to Promote Porcine Skin Wound Repair
Abstract Impaired skin healing and progression into chronic wounds is a prevalent and growing medical problem. Porous, resorbable …
Kupffer cell release of platelet activating factor drives dose limiting toxicities of nucleic acid nanocarriers
High CD8 T-Cell Receptor Clonality and Altered CDR3 Properties Are Associated With Elevated Isolevuglandins in Adipose Tissue During Diet-Induced Obesity
High CD8 T-Cell Receptor Clonality and Altered CDR3 Properties Are Associated With Elevated Isolevuglandins in Adipose Tissue During Diet-Induced Obesity
Links between Immunologic Memory and Metabolic Cycling

Contact